Which acquisition thickness results in the highest spatial resolution?

Acquisition thickness is a critical factor in determining spatial resolution in computed tomography (CT) imaging. The thinner the slices, the better the spatial resolution, allowing for more precise differentiation of adjacent structures within the image. When using 0.625 mm thickness, this is the thinnest option available among the choices provided. This allows for improved detail and the ability to visualize smaller anatomical features that might be missed with thicker acquisitions.

As the acquisition thickness increases, such as with the options of 1.25 mm, 2.5 mm, or 3.75 mm, the potential for spatial resolution decreases. Thicker slices can lead to partial volume effects, where different tissue types are averaged together, obscuring the fine details critical for accurate interpretation of imaging studies. Therefore, the choice of 0.625 mm is optimal for achieving the highest spatial resolution in CT imaging.